 September 11, 1966 Major League Debut 2IP 3K |
 June 1, 1968 1st Career RBI No Decision 6.2IP 7K |
 July 29, 1968 My Birthday Loss #10 7.2IP 7K |
 April 25, 1970 Loss #14 8IP 5K |
 May 24, 1970 Win #15 9IP 8K |
 August 4, 1970 2nd Career Shutout Win #18 9IP 13K |
 August 22, 1970 Blown Save .2IP 0K |
 June 20, 1971 No Decision 5.2IP 7K |
 June 30, 1971 1st Career Triple Win #27 7IP 9K |
 July 5, 1971 Loss #29 7.2IP 5K |
 July 23, 1971 Loss #32 4IP 1K |
 July 29, 1971 My Birthday No Decision 5IP 3K |
 August 3, 1971 Loss #33 7IP 3K |
 July 19, 1973 Loss #66 10.1IP 13K |
 April 5, 1974 Win #70 8IP 5K |
 July 1, 1974 Loss #77 9IP 10K |
 August 7, 1974 Loss #82 8.2IP 13K |
 September 15, 1974 Win #89 9IP 7K |
 September 15, 1974 Win #89 9IP 7K |
 April 7, 1975 Win #92 9IP 12K |
 July 30, 1975 Win #103 9IP 5K |
 August 24, 1975 Win #105 6IP 8K |
 June 6, 1976 Loss #105 3.1IP 3K |
 June 11, 1976 No Decision 5IP 9K |
 June 19, 1976 Win #111 9IP 15K |
 June 26, 1976 Loss #106 5IP 8K |
 September 29, 1976 Win #121 9IP 8K |
 April 30, 1977 Loss #119 9.1IP 13K |
 May 19, 1977 Win #128 9IP 12K |
 May, 29, 1977 Win #130 9IP 12K |
 June 4, 1977 2200th Strikeout Loss #121 7.2IP 11K |
 June 12, 1977 Win #131 6.2IP 10K |
 July 30, 1977 Loss #126 9IP 6K |
 August 13, 1977 Win #133 11IP 11K |
 August 24, 1977 Loss #128 9IP 10K |
 September 19, 1977 Loss #131 5IP 5K |
 July 14, 1978 No Decision 9IP 13K |
 July 19, 1978 Win #145 9IP 10K |
 September 24, 1978 Win #150 7IP 6K |
 April 21, 1979 Win #154 7.2IP 12K |
 April 26, 1979 No Decision 2IP 2K |
 June 9, 1979 Win #158 9IP 16K |
 June 22, 1979 Loss #149 6.1IP 9K |
 July 5, 1979 Loss #151 9IP 5K |
 September 24, 1979 Last Angels Win Win #167 9IP 8K |
 April 17, 1980 No Decision 6IP 5K |
 June 19, 1980 Win #172 7IP 7K |
 June 24, 1980 No Decision 8IP 5K |
 July 4, 1980 3000th Strikeout Cesar Geronimo Loss #165 4.1IP 6K |
 July 15, 1980 No Decision 8IP 2K |
 May 16, 1981 Win #181 7IP 8K |
 May 26, 1981 Win #182 7IP 6K |
 June 5, 1981 Win #183 9IP 10K |
 June 10, 1981 No Decision 7.2IP 8K |
 September 15, 1981 Loss #174 6IP 4K |
 September 26, 1981 5th No Hitter Win #188 9IP 11K |
 October 1, 1981 Win #189 9IP 9K |
 April 6, 1982 Loss #175 3IP 5K |
 April 11, 1982 Loss #176 5IP 3K |
 April 16, 1982 Loss #177 5.2IP 6K |
 April 21, 1982 Loss #178 6.2IP 4K |
 May 11, 1982 Win #192 5IP 4K |
 May 22, 1982 No Decision 8IP 10K |
 June 18, 1982 Win #195 9IP 11K |
 June 23, 1982 No Decision 4.2IP 3Ks |
 July 9, 1982 Loss #183 9IP 10K |
 July 16, 1982 Win #198 9IP 11K |
 August 1, 1982 No Decision 9IP 6K |
 August 21, 1982 Win #202 9IP 5K |
 August 31, 1982 Win #203 9IP 9K |
 September 10, 1982 Loss #185 9IP 9K |
 September 15, 1982 Win #204 8IP 4K |
 October 1, 1982 Loss #186 8IP 10K |
 May 2, 1983 Win #208 7.2IP 12K |
 June 28, 1983 Win #211 8IP 5K |
 August 7, 1983 Win #216 9IP 8K |
 August 21, 1983 Loss #192 6IP 5K |
 September 20, 1983 Win #219 6IP 7K |
 April 10, 1984 Loss #196 7IP 11K |
 April 20, 1984 No Decision 3IP 2K |
 April 25, 1984 Loss #197 7IP 4K |
 August 22, 1984 Win #230 9IP 12K |
 April 9, 1985 Win #232 7IP 4K |
 April 19, 1985 Loss #207 4.1IP 1K |
 April 28, 1985 No Decision 7IP 7K |
 May 3, 1985 No Decision 6IP 10K |
 May 24, 1985 Win #235 9IP 7K |
 July 11, 1985 4000th Strikeout Danny Heep No Decision 7IP 11K |
 July 11, 1985 4000th Strikeout Danny Heep No Decision 7IP 11K |
 August 3, 1985 No Decision 7IP 8K |
 October 5, 1985 Win #241 7IP 8K |
 April 12, 1986 Win #242 7IP 5K |
 April 21, 1986 Loss #220 3IP 4K |
 April 29, 1986 Loss #221 1IP 2K |
 May 7, 1986 Loss #222 5IP 3K |
 July 27, 1986 Win #248 5IP 10K |
 August 17, 1986 No Decision 5IP 5K |
 August 27, 1986 Win #250 6IP 5K |
 June 2, 1987 Loss #231 2IP 3K |
 July 3, 1987 Loss #235 7.1IP 10K |
 July 29, 1987 My Birthday Loss #239 5.1IP 5K |
 June 7, 1987 Win #256 7IP 12K |
 September 14, 1987 Win #261 6.2IP 9K |
 May 29, 1988 Win #266 7.1IP 4K |
 June 4, 1988 Win #245 5IP 10K |
 July 9, 1988 100th Win As Astros Win #267 7.1IP 5K |
 August 24, 1988 No Decision 6IP 9K |
 September 14, 1988 Last Astros Win Win #273 9IP 13K |
 April 6, 1989 1st Rangers Game No Decision 5IP 8K |
 April 30, 1989 1st Matchup vs Roger Clemens Win #276 8IP 11K |
 April 30, 1989 1st Matchup vs Roger Clemens Win #276 8IP 11K |
 May 5, 1989 2nd Matchup vs Roger Clemens Loss #255 6.1IP 3K |
 June 14, 1989 Win #281 8.2IP 8K |
 July 6, 1989 Win #283 9IP 12K |
 July 20, 1989 Win #256 7.1IP 11K |
 July 30, 1989 Win #285 7.1IP 10K |
 August 5, 1989 Game #700 Walk #2500 Loss #260 7IP 8K |
 August 22, 1989 5000th Strikeout Rickey Henderson Loss #275 9IP 13K |
 August 27, 1989 Loss #262 8.1IP 11K |
 September 7, 1989 Loss #263 6.1IP 10K |
 April 9, 1990 Win #290 5IP 4K |
 April 14, 1990 Win #291 7IP 4K |
 May 8, 1990 Loss #265 2IP 1K |
 June 6, 1990 Loss #266 5IP 8K |
June 6, 1990 Loss #266 5IP 8K |
 June 11, 1990 6th No Hitter Win #294 9IP 14K |
 June 16, 1990 Loss #267 5IP 9K |
 July 7, 1990 Win #297 7IP 12K |
 July 14, 1990 Win #298 5.2IP 6K |
 July 20, 1990 Win #299 6IP 4K |
 July 25, 1990 No Decision 8IP 9K |
 July 31, 1990 Win #300 7.2IP 8K |
 August 5, 1990 Loss #268 9IP 5K |
 August 22, 1990 Win #301 7IP 5K |
 September 3, 1990 Win #302 8IP 8K |
 September 24, 1990 Loss #271 9IP 11K |
 September 30, 1990 Loss #272 7.1IP 11K |
 April 8, 1991 Opening Day Loss #273 7IP 9K |
 May 1, 1991 7th No Hitter Win #305 9IP 16K |
 June 6, 1991 No Decision 7IP 9K |
 June 11, 1991 Final Shutout (#61) Win #306 9IP 10K |
 July 7, 1991 Win #307 8.1IP 14K |
 July 23, 1991 Nolan Ryan 308th Win / Goose Gossage 308th Save Win #308 7IP 7K |
 July 28, 1991 Win #309 5.1IP 10K |
 September 12, 1991 Win #312 7IP 9K |
 September 19, 1991 Win #313 6IP 7K |
 September 25, 1991 Win #314 8IP 8K |
 September 30, 1991 5500th Strikeout Tino Martinez No Decision 6IP 6K |
 April 6, 1992 Opening Day vs Randy Johnson No Decision 4.2IP 4K |
 April 30, 1992 Loss #279 2.1IP 3K |
 June 17, 1992 Complete Game Loss Loss #281 8IP 8K |
 June 28, 1992 Win #315 7IP 7K |
 July 4, 1992 Last Complete Game Win #316 9IP 13K |
 July 4, 1992 Last Complete Game Win #316 9IP 13K |
 July 26, 1992 Win #319 7IP 5K |
 August 21, 1992 Loss #285 4.1IP 1K |
 September 22, 1992 No Decision 6IP 4K |
 August 1, 1992 Loss #282 5.1IP 7K |
 August 6, 1992 Only Career Ejection Loss #283 7.2IP 13K |
 August 16, 1992 Loss #284 4.2IP 5K |
 September 7, 1992 3rd Matchup vs Roger Clemens Loss #287 8.1IP 6K |
 September 27, 1992 Matchup vs Randy Johnson No Decision for either Ryan 7IP 5K; Johnson 8IP 18K |
 September 27, 1992 Matchup vs Randy Johnson No Decision for either Ryan 7IP 5K; Johnson 8IP 18K |
 April 9, 1993 Win #320 6IP 5K |
 July 19, 1993 Win #321 5.2IP 6K |
 August 4, 1993 Ryan vs Ventura Win #322 7IP 5K |
 August 21, 1993 No Decision 3IP 1K |
 August 15, 1993 Last Win Win #324 7IP 2K |
 August 15, 1993 Last Win ( Inscribed "324th Win" ) Win #324 7IP 2K |
 August 15, 1993 Last Win ( Inscribed "Final Victory" ) Win #324 7IP 2K |
 September 12, 1993 Loss #291 5.2IP 3K |
 September 17, 1993 Last Strikeout No Decision 7IP 5K |
 September 22, 1993 Last Game Pitched Lost #292 0IP 0K |
